Skip to Content

Gold-standard DNA sequencing 
for precise genetic insights

 
Precision in Every Base: Sanger Sequencing for Unmatched Genetic Accuracy

Introduction

Sanger Sequencing, also known as the chain-termination method, continues to be the gold standard for DNA sequencing, renowned for its exceptional accuracy and reliability. At Scan Diagnostic Laboratory, we harness this advanced technique to provide precise genetic insights across a wide range of applications, including clinical diagnostics, biomedical research, forensics, and personalized medicine.

Our state-of-the-art sequencing platform is designed to deliver high-quality results, ensuring the identification of genetic mutations, polymorphisms, and disease-related variations with unparalleled precision. Whether validating findings from Next-Generation Sequencing (NGS), conducting targeted mutation analysis, or performing small-scale sequencing projects, our expertise and cutting-edge technology ensure reliable and actionable outcomes.

With a commitment to excellence in genetic testing, Scan Diagnostic Laboratory empowers healthcare providers, researchers, and forensic experts with the data needed to make informed decisions, driving advancements in medicine and life sciences.

Why Sanger Sequencing?

Sanger Sequencing is a trusted and widely used DNA sequencing method, ideal for:

Identifying genetic mutations and polymorphisms – crucial for disease diagnosis and treatment.
Validating Next-Generation Sequencing (NGS) results – ensuring accuracy in genetic research.
Supporting clinical diagnostics – aiding genetic and hereditary disease screening.
Providing high-precision sequencing for targeted analysis – perfect for small-scale projects.

Methods & Technologies

Our advanced Sanger Sequencing workflow integrates cutting-edge technologies to deliver reliable genetic data:


Chain-Termination Method

Incorporating dideoxynucleotides (ddNTPs) to halt DNA synthesis at precise locations.


Capillary Electrophoresis

High-resolution separation of DNA fragments for base-by-base accuracy.


High-Throughput Platforms

Enhancing speed and cost-effectiveness for diverse sequencing needs. .

Applications of Sanger Sequencing

Sanger Sequencing plays a vital role across multiple disciplines:


🏥 Clinical Diagnostics

  • Detecting genetic disorders, cancer mutations, and hereditary diseases.

🔬 Biomedical Research

  • Studying gene functions, mutations, and evolutionary patterns.

🧬 Forensic Science

  • DNA profiling, paternity testing, and criminal investigations.

🌱 Agriculture & Livestock

  • Genetic marker analysis for improved breeding and crop enhancements.

Future of Sanger Sequencing

While NGS has transformed genomics, Sanger Sequencing continues to evolve with: 

🚀 Integration with NGS

  • Used for precise validation and targeted sequencing.

Automation & AI-Driven Analysis

  • Enhancing speed and accuracy.

🛠 Portable Sequencing Technologies

  • Bringing genetic testing to the point of care.

Discover our key benefits

1

Unmatched 
Accuracy

Recognized as the gold standard in DNA sequencing, ensuring precise and high-fidelity genetic analysis.

2

Reliable & 
Proven
 

A trusted method, widely used in clinical diagnostics, research, and forensic investigations.

3

Cost-Effective for 
Small-Scale Projects 

Ideal for mutation detection, polymorphism analysis, and NGS validation without large-scale sequencing.

4

Expert Support & Consultation

Comprehensive analysis from sample preparation to result interpretation.

Our Sequencing Process

1

Consultation

Understanding project needs and sequencing objectives.

2

Sample Preparation

Ensuring high-quality DNA extraction and purification.

3

Sanger Sequencing

Running samples through state-of-the-art sequencing platforms.

4

Data Analysis & Reporting

Generating high-accuracy genetic reports with actionable insights.

5

Ongoing Support

Post-analysis consultation and technical guidance.

Our Comprehensive Range of
Sanger Sequencing Services

 ✔ Single read sequencing

✔  Microbial identification

✔  Fungal Identification (18S rRNA or ITS)

✔  Bacterial Identification (16S rRNA)

✔  Cloning of PCR products

✔  DNA fragments cloning

✔  Primer walking projects

✔  High-throughput sequencing (MTP in 96 well formats)

✔  Yeast Sequencing (18S or ITS or 26s rDNA)

✔  PCR amplification and purification

✔  Primer design & synthesis

✔  Genes and/or genomic regions re-sequencing

✔  DNA isolation, including large constructs

✔  Small Plasmid & Large Plasmid Sequencing

✔  Library services (normalised cDNA, shotgun, cosmid/fosmid)

 Custom Sequencing Solutions for Specialized Needs

At Scan Diagnostic Laboratory,

we provide high-precision Sanger Sequencing to support your research and diagnostic needs. Our advanced sequencing technology ensures accurate, high-quality DNA sequencing results for a wide range of applications, including genetic analysis, mutation detection, and microbial identification. Whether you need single-gene sequencing or full-genome validation, our expert team ensures reliable data with fast turnaround times.

📩 Contact us today for precise and efficient Sanger Sequencing services tailored to your research needs! 💬

📩 


Get in touch today
 

Contact us